(Matrex® Metoject® , Methotrexate)
Available as tablets or capsules.
Available as soluble tablets?
Available as a liquid?
Yes - oral solution
Available as something for placing under your tongue?
Available as something for placing on your gum?
Available as a patch for putting on your skin?
Available as an injection?
Available as nasal/oral spray?
Safe or appropriate to crush
Tablets should not be crushed as the medication is cytotoxic. Use liquid alternative.
Additional information for Healthcare Professionals+
Usual formulation brand names
Is tablet/capsule specially coated?
Sublingual/buccal formulation strength
Transdermal patch strength
1mg/40ml, 5mg/2ml, 7.5mg/0.3ml, 10mg/0.4ml, 12.5mg/0.5ml, 15mg/0.6ml, 17.5mg/0.7ml, 20mg/0.8ml, 22.5mg/0.9ml, 25mg/ml, 50mg/2ml, 500mg/20ml
Nasal/oral spray Strength
Available as a licensed liquid or special?
Are specials or imports available?
N/A licensed alternative available
Is the liquid medicine sugar free?
Yes some- check individual manufacturer information
Licensed for administration via enteral tube
Advice on administration via enteral tube
Current resources suggest that it is likely to be safe to administer the liquid via enteral feeding tubes, however this is an unlicensed use of the medication. Clinicians should refer to specialist resources for advice on how to administer this medication via enteral feeding tubes.
Caution - cytotoxic.