As the graph below shows, some drugs, such as digoxin,
need to be taken for a few days before the amount in the body is sufficient
for it to work.
You can see that the amount of drug in the body gradually
builds up until it reaches the point at which it will be able to work
properly.

If drugs are taken more than once in a day
then as well as being more likely to forget to take them, you will experience
more 'peaks' ie times when side effects are more likely.
The graph shows what the amount of drug in the body looks
like when you take your medicine 4 times a day. You can see that there
are 4 peaks that would occur after each time you took the medicine.

By giving drugs in extended release formulations ie once
or twice a day, not only is it easier to remember to take them, but
you are also less likely to suffer side effects.
You can see on the graph that there are no sharp peaks
and the amount of drug in the body does not go above the point at which
side effects are likely.
